| Vestavia Hills to Southchase (Florida) | 472.63 mi (760.62 km) |
| Vestavia Hills to Southern Pines (North Carolina) | 435.63 mi (701.09 km) |
| Vestavia Hills to Southfield (Michigan) | 651.61 mi (1,048.67 km) |
| Vestavia Hills to Southgate (Michigan) | 634.68 mi (1,021.41 km) |
| Vestavia Hills to Southlake (Texas) | 602.36 mi (969.41 km) |
| Vestavia Hills to Spanaway (Washington) | 2,079.67 mi (3,346.90 km) |
| Vestavia Hills to Spanish Fork (Utah) | 1,446.83 mi (2,328.45 km) |
| Vestavia Hills to Spanish Lake (Missouri) | 416.25 mi (669.88 km) |
| Vestavia Hills to Spanish Springs (Nevada) | 1,865.88 mi (3,002.85 km) |
| Vestavia Hills to Sparks (Nevada) | 1,868.09 mi (3,006.40 km) |
| Vestavia Hills to Spartanburg (South Carolina) | 294.00 mi (473.15 km) |
| Vestavia Hills to Spearfish (South Dakota) | 1,188.50 mi (1,912.71 km) |
| Vestavia Hills to Speedway (Indiana) | 439.04 mi (706.57 km) |
| Vestavia Hills to Spencer (Iowa) | 809.37 mi (1,302.55 km) |
| Vestavia Hills to Spokane (Washington) | 1,868.30 mi (3,006.75 km) |
