| Vandalia to Oskaloosa (Iowa) | 453.68 mi (730.12 km) |
| Vandalia to Oswego (Illinois) | 250.06 mi (402.43 km) |
| Vandalia to Oswego (New York) | 467.23 mi (751.93 km) |
| Vandalia to Otsego (Minnesota) | 606.45 mi (975.98 km) |
| Vandalia to Ottawa (Illinois) | 263.49 mi (424.05 km) |
| Vandalia to Ottawa (Kansas) | 598.58 mi (963.33 km) |
| Vandalia to Ottumwa (Iowa) | 439.43 mi (707.20 km) |
| Vandalia to Overland (Missouri) | 340.14 mi (547.41 km) |
| Vandalia to Overland Park (Kansas) | 564.26 mi (908.09 km) |
| Vandalia to Overlea (Maryland) | 409.91 mi (659.69 km) |
| Vandalia to Oviedo (Florida) | 793.93 mi (1,277.71 km) |
| Vandalia to Owasso (Oklahoma) | 679.17 mi (1,093.02 km) |
| Vandalia to Owatonna (Minnesota) | 547.39 mi (880.94 km) |
| Vandalia to Owensboro (Kentucky) | 215.08 mi (346.13 km) |
| Vandalia to Owings Mills (Maryland) | 395.00 mi (635.69 km) |
