| Van Buren to Southchase (Florida) | 902.36 mi (1,452.20 km) |
| Van Buren to Southern Pines (North Carolina) | 842.13 mi (1,355.28 km) |
| Van Buren to Southfield (Michigan) | 767.58 mi (1,235.30 km) |
| Van Buren to Southgate (Michigan) | 759.12 mi (1,221.69 km) |
| Van Buren to Southlake (Texas) | 235.02 mi (378.23 km) |
| Van Buren to Spanaway (Washington) | 1,652.18 mi (2,658.92 km) |
| Van Buren to Spanish Fork (Utah) | 995.54 mi (1,602.17 km) |
| Van Buren to Spanish Lake (Missouri) | 324.60 mi (522.39 km) |
| Van Buren to Spanish Springs (Nevada) | 1,411.92 mi (2,272.27 km) |
| Van Buren to Sparks (Nevada) | 1,414.03 mi (2,275.66 km) |
| Van Buren to Spartanburg (South Carolina) | 702.09 mi (1,129.91 km) |
| Van Buren to Spearfish (South Dakota) | 799.73 mi (1,287.04 km) |
| Van Buren to Speedway (Indiana) | 535.24 mi (861.39 km) |
| Van Buren to Spencer (Iowa) | 533.63 mi (858.79 km) |
| Van Buren to Spokane (Washington) | 1,452.57 mi (2,337.69 km) |
