| Valley Center to Enterprise (Nevada) | 217.07 mi (349.35 km) |
| Valley Center to Enumclaw (Washington) | 999.64 mi (1,608.77 km) |
| Valley Center to Ephrata (Pennsylvania) | 2,291.39 mi (3,687.64 km) |
| Valley Center to Erie (Colorado) | 812.49 mi (1,307.58 km) |
| Valley Center to Erie (Pennsylvania) | 2,093.18 mi (3,368.65 km) |
| Valley Center to Erlanger (Kentucky) | 1,843.10 mi (2,966.19 km) |
| Valley Center to Escanaba (Michigan) | 1,799.82 mi (2,896.52 km) |
| Valley Center to Escondido (California) | 7.53 mi (12.12 km) |
| Valley Center to Española (New Mexico) | 650.82 mi (1,047.39 km) |
| Valley Center to Essex (Maryland) | 2,279.17 mi (3,667.97 km) |
| Valley Center to Essex Junction (Vermont) | 2,453.59 mi (3,948.67 km) |
| Valley Center to Estelle (Louisiana) | 1,597.58 mi (2,571.05 km) |
| Valley Center to Estero (Florida) | 2,152.13 mi (3,463.51 km) |
| Valley Center to Euclid (Ohio) | 2,015.98 mi (3,244.40 km) |
| Valley Center to Eufaula (Alabama) | 1,850.49 mi (2,978.07 km) |
