| Valletta to Southern Pines (North Carolina) | 5,042.39 mi (8,114.95 km) |
| Valletta to Southfield (Michigan) | 4,949.17 mi (7,964.92 km) |
| Valletta to Southgate (Michigan) | 4,956.83 mi (7,977.25 km) |
| Valletta to Southlake (Texas) | 5,948.83 mi (9,573.71 km) |
| Valletta to Spanaway (Washington) | 6,112.96 mi (9,837.86 km) |
| Valletta to Spanish Fork (Utah) | 6,169.84 mi (9,929.39 km) |
| Valletta to Spanish Lake (Missouri) | 5,393.48 mi (8,679.96 km) |
| Valletta to Spanish Springs (Nevada) | 6,457.83 mi (10,392.87 km) |
| Valletta to Sparks (Nevada) | 6,463.95 mi (10,402.72 km) |
| Valletta to Spartanburg (South Carolina) | 5,171.43 mi (8,322.61 km) |
| Valletta to Spearfish (South Dakota) | 5,675.52 mi (9,133.87 km) |
| Valletta to Speedway (Indiana) | 5,180.97 mi (8,337.97 km) |
| Valletta to Spencer (Iowa) | 5,412.84 mi (8,711.12 km) |
| Valletta to Spokane (Washington) | 5,945.76 mi (9,568.78 km) |
| Valletta to Spokane Valley (Washington) | 5,940.43 mi (9,560.19 km) |
