| Upton to Seymour (Tennessee) | 3,918.75 mi (6,306.62 km) |
| Upton to Shady Hills (Florida) | 4,245.93 mi (6,833.16 km) |
| Upton to Shafter (California) | 5,209.18 mi (8,383.36 km) |
| Upton to Shaker Heights (Ohio) | 3,565.65 mi (5,738.36 km) |
| Upton to Shakopee (Minnesota) | 3,853.25 mi (6,201.20 km) |
| Upton to Sharon (Pennsylvania) | 3,536.07 mi (5,690.75 km) |
| Upton to Sharonville (Ohio) | 3,778.87 mi (6,081.51 km) |
| Upton to Shasta Lake (California) | 5,003.97 mi (8,053.11 km) |
| Upton to Shawnee (Kansas) | 4,184.41 mi (6,734.15 km) |
| Upton to Shawnee (Oklahoma) | 4,451.59 mi (7,164.14 km) |
| Upton to Sheboygan (Wisconsin) | 3,694.33 mi (5,945.45 km) |
| Upton to Shelby (North Carolina) | 3,859.53 mi (6,211.31 km) |
| Upton to Shelbyville (Indiana) | 3,819.60 mi (6,147.05 km) |
| Upton to Shelbyville (Kentucky) | 3,862.42 mi (6,215.96 km) |
| Upton to Shelbyville (Tennessee) | 4,042.87 mi (6,506.37 km) |
