| Upton to Olympia Heights (Florida) | 4,294.57 mi (6,911.45 km) |
| Upton to Omaha (Nebraska) | 4,116.92 mi (6,625.54 km) |
| Upton to On Top of the World Designated Place (Florida) | 4,199.36 mi (6,758.22 km) |
| Upton to Onalaska (Wisconsin) | 3,814.32 mi (6,138.56 km) |
| Upton to Oneida (New York) | 3,264.94 mi (5,254.42 km) |
| Upton to Oneonta (New York) | 3,268.83 mi (5,260.67 km) |
| Upton to Ontario (California) | 5,241.45 mi (8,435.30 km) |
| Upton to Ontario (Oregon) | 4,657.09 mi (7,494.86 km) |
| Upton to Opa-locka (Florida) | 4,282.01 mi (6,891.22 km) |
| Upton to Opelika (Alabama) | 4,142.66 mi (6,666.97 km) |
| Upton to Opelousas (Louisiana) | 4,516.41 mi (7,268.45 km) |
| Upton to Orange (California) | 5,261.85 mi (8,468.13 km) |
| Upton to Orange (Texas) | 4,602.86 mi (7,407.58 km) |
| Upton to Orange City (Florida) | 4,167.60 mi (6,707.10 km) |
| Upton to Orangeburg (South Carolina) | 3,920.93 mi (6,310.12 km) |
