| Two Rivers to Santa Paula (California) | 1,801.67 mi (2,899.50 km) |
| Two Rivers to Santa Rosa (California) | 1,850.53 mi (2,978.14 km) |
| Two Rivers to Santaquin (Utah) | 1,270.16 mi (2,044.13 km) |
| Two Rivers to Santee (California) | 1,758.25 mi (2,829.62 km) |
| Two Rivers to Sapulpa (Oklahoma) | 720.02 mi (1,158.76 km) |
| Two Rivers to Saraland (Alabama) | 919.97 mi (1,480.55 km) |
| Two Rivers to Sarasota (Florida) | 1,195.24 mi (1,923.55 km) |
| Two Rivers to Sarasota Springs (Florida) | 1,198.16 mi (1,928.26 km) |
| Two Rivers to Saratoga (California) | 1,850.83 mi (2,978.63 km) |
| Two Rivers to Saratoga Springs (New York) | 693.85 mi (1,116.65 km) |
| Two Rivers to Saratoga Springs (Utah) | 1,267.08 mi (2,039.17 km) |
| Two Rivers to Sartell (Minnesota) | 340.18 mi (547.46 km) |
| Two Rivers to Satellite Beach (Florida) | 1,169.52 mi (1,882.16 km) |
| Two Rivers to Sauk Rapids (Minnesota) | 336.69 mi (541.85 km) |
| Two Rivers to Sault Ste. Marie (Michigan) | 223.87 mi (360.28 km) |
