| Twinsburg to University Place (Washington) | 2,049.15 mi (3,297.80 km) |
| Twinsburg to Upland (California) | 2,025.12 mi (3,259.11 km) |
| Twinsburg to Upper Arlington (Ohio) | 123.52 mi (198.78 km) |
| Twinsburg to Upper Grand Lagoon (Florida) | 807.07 mi (1,298.86 km) |
| Twinsburg to Upper Montclair (New Jersey) | 378.63 mi (609.34 km) |
| Twinsburg to Urbana (Illinois) | 363.27 mi (584.63 km) |
| Twinsburg to Urbana (Maryland) | 256.27 mi (412.43 km) |
| Twinsburg to Urbana (Ohio) | 147.14 mi (236.80 km) |
| Twinsburg to Urbandale (Iowa) | 638.39 mi (1,027.39 km) |
| Twinsburg to Utica (New York) | 340.96 mi (548.72 km) |
| Twinsburg to Uvalde (Texas) | 1,325.24 mi (2,132.76 km) |
| Twinsburg to Vacaville (California) | 2,139.96 mi (3,443.94 km) |
| Twinsburg to Vadnais Heights (Minnesota) | 639.39 mi (1,029.00 km) |
| Twinsburg to Vail (Arizona) | 1,733.25 mi (2,789.39 km) |
| Twinsburg to Valdosta (Georgia) | 730.69 mi (1,175.93 km) |
