| Twinsburg to Siloam Springs (Arkansas) | 788.28 mi (1,268.61 km) |
| Twinsburg to Silver Firs (Washington) | 2,028.24 mi (3,264.13 km) |
| Twinsburg to Silver Spring (Maryland) | 283.23 mi (455.82 km) |
| Twinsburg to Silver Springs Shores (Florida) | 844.19 mi (1,358.60 km) |
| Twinsburg to Silverdale (Washington) | 2,053.63 mi (3,305.00 km) |
| Twinsburg to Silverton (Oregon) | 2,075.88 mi (3,340.81 km) |
| Twinsburg to Simi Valley (California) | 2,077.27 mi (3,343.04 km) |
| Twinsburg to Simpsonville (South Carolina) | 457.68 mi (736.57 km) |
| Twinsburg to Sioux City (Iowa) | 771.72 mi (1,241.96 km) |
| Twinsburg to Sioux Falls (South Dakota) | 793.26 mi (1,276.62 km) |
| Twinsburg to Skokie (Illinois) | 328.49 mi (528.66 km) |
| Twinsburg to Sleepy Hollow (New York) | 393.84 mi (633.82 km) |
| Twinsburg to Slidell (Louisiana) | 893.06 mi (1,437.24 km) |
| Twinsburg to Smithfield (North Carolina) | 434.84 mi (699.81 km) |
| Twinsburg to Smithfield (Utah) | 1,562.43 mi (2,514.49 km) |
