| Twinsburg to Scottsbluff (Nebraska) | 1,145.38 mi (1,843.31 km) |
| Twinsburg to Scottsboro (Alabama) | 524.94 mi (844.80 km) |
| Twinsburg to Scottsdale (Arizona) | 1,738.52 mi (2,797.88 km) |
| Twinsburg to Scranton (Pennsylvania) | 299.74 mi (482.39 km) |
| Twinsburg to Seabrook (Maryland) | 291.59 mi (469.27 km) |
| Twinsburg to Seabrook (Texas) | 1,112.10 mi (1,789.75 km) |
| Twinsburg to Seaford (New York) | 417.05 mi (671.17 km) |
| Twinsburg to Seagoville (Texas) | 1,023.84 mi (1,647.72 km) |
| Twinsburg to Seal Beach (California) | 2,057.15 mi (3,310.66 km) |
| Twinsburg to Searcy (Arkansas) | 697.70 mi (1,122.85 km) |
| Twinsburg to Seaside (California) | 2,173.13 mi (3,497.31 km) |
| Twinsburg to SeaTac (Washington) | 2,036.60 mi (3,277.59 km) |
| Twinsburg to Seattle (Washington) | 2,037.14 mi (3,278.45 km) |
| Twinsburg to Sebastian (Florida) | 937.10 mi (1,508.11 km) |
| Twinsburg to Sebring (Florida) | 956.60 mi (1,539.49 km) |
