| Twinsburg to Santa Paula (California) | 2,091.15 mi (3,365.38 km) |
| Twinsburg to Santa Rosa (California) | 2,176.01 mi (3,501.95 km) |
| Twinsburg to Santaquin (Utah) | 1,585.64 mi (2,551.85 km) |
| Twinsburg to Santee (California) | 2,028.43 mi (3,264.44 km) |
| Twinsburg to Sapulpa (Oklahoma) | 870.17 mi (1,400.40 km) |
| Twinsburg to Saraland (Alabama) | 812.88 mi (1,308.20 km) |
| Twinsburg to Sarasota (Florida) | 968.16 mi (1,558.10 km) |
| Twinsburg to Sarasota Springs (Florida) | 969.98 mi (1,561.04 km) |
| Twinsburg to Saratoga (California) | 2,168.00 mi (3,489.06 km) |
| Twinsburg to Saratoga Springs (New York) | 410.43 mi (660.52 km) |
| Twinsburg to Saratoga Springs (Utah) | 1,586.12 mi (2,552.62 km) |
| Twinsburg to Sartell (Minnesota) | 704.98 mi (1,134.55 km) |
| Twinsburg to Satellite Beach (Florida) | 909.40 mi (1,463.53 km) |
| Twinsburg to Sauk Rapids (Minnesota) | 701.45 mi (1,128.88 km) |
| Twinsburg to Sault Ste. Marie (Michigan) | 385.06 mi (619.70 km) |
