| Twinsburg to Oskaloosa (Iowa) | 580.65 mi (934.47 km) |
| Twinsburg to Oswego (Illinois) | 357.41 mi (575.20 km) |
| Twinsburg to Oswego (New York) | 292.03 mi (469.98 km) |
| Twinsburg to Otsego (Minnesota) | 669.27 mi (1,077.09 km) |
| Twinsburg to Ottawa (Illinois) | 382.79 mi (616.04 km) |
| Twinsburg to Ottawa (Kansas) | 754.68 mi (1,214.54 km) |
| Twinsburg to Ottumwa (Iowa) | 570.73 mi (918.51 km) |
| Twinsburg to Overland (Missouri) | 505.59 mi (813.68 km) |
| Twinsburg to Overland Park (Kansas) | 718.95 mi (1,157.04 km) |
| Twinsburg to Overlea (Maryland) | 292.57 mi (470.85 km) |
| Twinsburg to Oviedo (Florida) | 875.12 mi (1,408.37 km) |
| Twinsburg to Owasso (Oklahoma) | 847.70 mi (1,364.24 km) |
| Twinsburg to Owatonna (Minnesota) | 627.59 mi (1,010.01 km) |
| Twinsburg to Owensboro (Kentucky) | 389.72 mi (627.19 km) |
| Twinsburg to Owings Mills (Maryland) | 278.23 mi (447.77 km) |
