| Twinsburg to Olympia (Washington) | 2,066.41 mi (3,325.57 km) |
| Twinsburg to Olympia Heights (Florida) | 1,079.57 mi (1,737.40 km) |
| Twinsburg to Omaha (Nebraska) | 757.45 mi (1,219.00 km) |
| Twinsburg to On Top of the World Designated Place (Florida) | 845.38 mi (1,360.51 km) |
| Twinsburg to Onalaska (Wisconsin) | 526.78 mi (847.78 km) |
| Twinsburg to Oneida (New York) | 319.78 mi (514.64 km) |
| Twinsburg to Oneonta (New York) | 337.21 mi (542.68 km) |
| Twinsburg to Ontario (California) | 2,024.61 mi (3,258.30 km) |
| Twinsburg to Ontario (Oregon) | 1,800.52 mi (2,897.65 km) |
| Twinsburg to Opa-locka (Florida) | 1,067.74 mi (1,718.37 km) |
| Twinsburg to Opelika (Alabama) | 636.33 mi (1,024.08 km) |
| Twinsburg to Opelousas (Louisiana) | 952.69 mi (1,533.21 km) |
| Twinsburg to Orange (California) | 2,042.73 mi (3,287.46 km) |
| Twinsburg to Orange (Texas) | 1,035.13 mi (1,665.89 km) |
| Twinsburg to Orange City (Florida) | 855.92 mi (1,377.47 km) |
