| Twinsburg to Enterprise (Nevada) | 1,846.94 mi (2,972.36 km) |
| Twinsburg to Enumclaw (Washington) | 2,023.15 mi (3,255.94 km) |
| Twinsburg to Ephrata (Pennsylvania) | 286.52 mi (461.11 km) |
| Twinsburg to Erie (Colorado) | 1,235.64 mi (1,988.57 km) |
| Twinsburg to Erie (Pennsylvania) | 89.55 mi (144.12 km) |
| Twinsburg to Erlanger (Kentucky) | 230.20 mi (370.47 km) |
| Twinsburg to Escanaba (Michigan) | 416.26 mi (669.91 km) |
| Twinsburg to Escondido (California) | 2,024.22 mi (3,257.67 km) |
| Twinsburg to Española (New Mexico) | 1,373.08 mi (2,209.76 km) |
| Twinsburg to Essex (Maryland) | 298.06 mi (479.67 km) |
| Twinsburg to Essex Junction (Vermont) | 474.74 mi (764.01 km) |
| Twinsburg to Estelle (Louisiana) | 929.15 mi (1,495.33 km) |
| Twinsburg to Estero (Florida) | 1,029.30 mi (1,656.49 km) |
| Twinsburg to Euclid (Ohio) | 18.93 mi (30.46 km) |
| Twinsburg to Eufaula (Alabama) | 681.80 mi (1,097.25 km) |
