| Tuscaloosa to Santa Paula (California) | 1,805.30 mi (2,905.35 km) |
| Tuscaloosa to Santa Rosa (California) | 1,990.66 mi (3,203.66 km) |
| Tuscaloosa to Santaquin (Utah) | 1,418.86 mi (2,283.43 km) |
| Tuscaloosa to Santee (California) | 1,700.64 mi (2,736.92 km) |
| Tuscaloosa to Sapulpa (Oklahoma) | 523.56 mi (842.59 km) |
| Tuscaloosa to Saraland (Alabama) | 168.30 mi (270.86 km) |
| Tuscaloosa to Sarasota (Florida) | 504.18 mi (811.40 km) |
| Tuscaloosa to Sarasota Springs (Florida) | 508.29 mi (818.02 km) |
| Tuscaloosa to Saratoga (California) | 1,955.50 mi (3,147.08 km) |
| Tuscaloosa to Saratoga Springs (New York) | 1,007.32 mi (1,621.12 km) |
| Tuscaloosa to Saratoga Springs (Utah) | 1,430.46 mi (2,302.10 km) |
| Tuscaloosa to Sartell (Minnesota) | 926.39 mi (1,490.88 km) |
| Tuscaloosa to Satellite Beach (Florida) | 539.46 mi (868.18 km) |
| Tuscaloosa to Sauk Rapids (Minnesota) | 923.74 mi (1,486.61 km) |
| Tuscaloosa to Sault Ste. Marie (Michigan) | 930.23 mi (1,497.06 km) |
