| Tuscaloosa to Oskaloosa (Iowa) | 623.39 mi (1,003.26 km) |
| Tuscaloosa to Oswego (Illinois) | 585.42 mi (942.15 km) |
| Tuscaloosa to Oswego (New York) | 923.14 mi (1,485.65 km) |
| Tuscaloosa to Otsego (Minnesota) | 892.24 mi (1,435.92 km) |
| Tuscaloosa to Ottawa (Illinois) | 565.59 mi (910.23 km) |
| Tuscaloosa to Ottawa (Kansas) | 569.53 mi (916.58 km) |
| Tuscaloosa to Ottumwa (Iowa) | 601.33 mi (967.76 km) |
| Tuscaloosa to Overland (Missouri) | 409.41 mi (658.89 km) |
| Tuscaloosa to Overland Park (Kansas) | 558.61 mi (899.00 km) |
| Tuscaloosa to Overlea (Maryland) | 744.20 mi (1,197.68 km) |
| Tuscaloosa to Oviedo (Florida) | 490.85 mi (789.95 km) |
| Tuscaloosa to Owasso (Oklahoma) | 516.17 mi (830.70 km) |
| Tuscaloosa to Owatonna (Minnesota) | 810.25 mi (1,303.98 km) |
| Tuscaloosa to Owensboro (Kentucky) | 313.34 mi (504.26 km) |
| Tuscaloosa to Owings Mills (Maryland) | 733.49 mi (1,180.44 km) |
