| Tupelo to Spokane Valley (Washington) | 1,736.36 mi (2,794.40 km) |
| Tupelo to Spout Springs (North Carolina) | 554.58 mi (892.51 km) |
| Tupelo to Spring (Texas) | 485.46 mi (781.27 km) |
| Tupelo to Spring Creek (Nevada) | 1,532.10 mi (2,465.68 km) |
| Tupelo to Spring Hill (Florida) | 541.83 mi (871.98 km) |
| Tupelo to Spring Hill (Tennessee) | 144.87 mi (233.15 km) |
| Tupelo to Spring Lake (North Carolina) | 556.22 mi (895.15 km) |
| Tupelo to Spring Valley (California) | 1,625.60 mi (2,616.15 km) |
| Tupelo to Spring Valley (Nevada) | 1,498.95 mi (2,412.33 km) |
| Tupelo to Spring Valley (New York) | 929.91 mi (1,496.55 km) |
| Tupelo to Springboro (Ohio) | 441.92 mi (711.20 km) |
| Tupelo to Springdale (Arkansas) | 333.67 mi (536.99 km) |
| Tupelo to Springdale (New Jersey) | 850.42 mi (1,368.62 km) |
| Tupelo to Springdale (Ohio) | 419.22 mi (674.67 km) |
| Tupelo to Springfield (Illinois) | 383.51 mi (617.20 km) |
