| Tupelo to Shelbyville (Tennessee) | 154.64 mi (248.88 km) |
| Tupelo to Shelton (Connecticut) | 978.33 mi (1,574.47 km) |
| Tupelo to Shelton (Washington) | 1,988.18 mi (3,199.66 km) |
| Tupelo to Shenandoah (Louisiana) | 298.24 mi (479.97 km) |
| Tupelo to Shepherdsville (Kentucky) | 307.20 mi (494.39 km) |
| Tupelo to Sheridan (Wyoming) | 1,208.99 mi (1,945.68 km) |
| Tupelo to Sherman (Texas) | 454.29 mi (731.11 km) |
| Tupelo to Sherrelwood (Colorado) | 974.29 mi (1,567.97 km) |
| Tupelo to Sherwood (Arkansas) | 201.54 mi (324.35 km) |
| Tupelo to Sherwood (Oregon) | 1,947.44 mi (3,134.09 km) |
| Tupelo to Shiloh (Illinois) | 303.24 mi (488.01 km) |
| Tupelo to Shiloh (Ohio) | 456.42 mi (734.54 km) |
| Tupelo to Shiloh (Pennsylvania) | 765.81 mi (1,232.45 km) |
| Tupelo to Shirley (New York) | 976.75 mi (1,571.93 km) |
| Tupelo to Shively (Kentucky) | 316.34 mi (509.10 km) |
