| Tupelo to Secaucus (New Jersey) | 919.26 mi (1,479.40 km) |
| Tupelo to Security-Widefield (Colorado) | 938.46 mi (1,510.31 km) |
| Tupelo to Sedalia (Missouri) | 395.51 mi (636.51 km) |
| Tupelo to Sedro-Woolley (Washington) | 1,973.27 mi (3,175.67 km) |
| Tupelo to Seguin (Texas) | 630.35 mi (1,014.46 km) |
| Tupelo to Selden (New York) | 970.54 mi (1,561.93 km) |
| Tupelo to Selma (Alabama) | 161.22 mi (259.45 km) |
| Tupelo to Selma (California) | 1,738.65 mi (2,798.09 km) |
| Tupelo to Selma (Texas) | 647.90 mi (1,042.69 km) |
| Tupelo to Seminole (Florida) | 566.35 mi (911.45 km) |
| Tupelo to Seven Hills (Ohio) | 623.85 mi (1,003.98 km) |
| Tupelo to Seven Oaks (South Carolina) | 434.02 mi (698.49 km) |
| Tupelo to Severn (Maryland) | 745.86 mi (1,200.35 km) |
| Tupelo to Severna Park (Maryland) | 750.84 mi (1,208.35 km) |
| Tupelo to Sevierville (Tennessee) | 312.61 mi (503.09 km) |
