| Tupelo to Sacramento (California) | 1,834.32 mi (2,952.05 km) |
| Tupelo to Saddlebrooke (Arizona) | 1,279.95 mi (2,059.88 km) |
| Tupelo to Safety Harbor (Florida) | 560.58 mi (902.16 km) |
| Tupelo to Saginaw (Michigan) | 682.29 mi (1,098.05 km) |
| Tupelo to Saginaw (Texas) | 506.25 mi (814.73 km) |
| Tupelo to Sahuarita (Arizona) | 1,294.36 mi (2,083.07 km) |
| Tupelo to Saks (Alabama) | 169.32 mi (272.49 km) |
| Tupelo to Salem (Massachusetts) | 1,117.66 mi (1,798.71 km) |
| Tupelo to Salem (Ohio) | 629.11 mi (1,012.46 km) |
| Tupelo to Salem (Oregon) | 1,950.57 mi (3,139.14 km) |
| Tupelo to Salem (Virginia) | 528.87 mi (851.13 km) |
| Tupelo to Salem Lakes (Wisconsin) | 572.14 mi (920.78 km) |
| Tupelo to Salida (California) | 1,815.13 mi (2,921.18 km) |
| Tupelo to Salina (Kansas) | 584.13 mi (940.06 km) |
| Tupelo to Salinas (California) | 1,849.58 mi (2,976.61 km) |
