| Tupelo to McHenry (Illinois) | 558.05 mi (898.10 km) |
| Tupelo to McKeesport (Pennsylvania) | 643.31 mi (1,035.30 km) |
| Tupelo to McKinleyville (California) | 1,975.02 mi (3,178.49 km) |
| Tupelo to McKinney (Texas) | 461.75 mi (743.11 km) |
| Tupelo to McLean (Virginia) | 716.04 mi (1,152.36 km) |
| Tupelo to McMinnville (Oregon) | 1,962.18 mi (3,157.82 km) |
| Tupelo to McMinnville (Tennessee) | 193.61 mi (311.59 km) |
| Tupelo to McNair (Virginia) | 705.55 mi (1,135.48 km) |
| Tupelo to McPherson (Kansas) | 571.80 mi (920.22 km) |
| Tupelo to Mead Valley (California) | 1,629.46 mi (2,622.36 km) |
| Tupelo to Meadow Woods (Florida) | 596.43 mi (959.87 km) |
| Tupelo to Meadowbrook (Virginia) | 666.71 mi (1,072.97 km) |
| Tupelo to Meadville (Pennsylvania) | 691.10 mi (1,112.21 km) |
| Tupelo to Mebane (North Carolina) | 548.44 mi (882.63 km) |
| Tupelo to Mechanicsville (Virginia) | 676.70 mi (1,089.04 km) |
