| Tupelo to Lovington (New Mexico) | 844.54 mi (1,359.15 km) |
| Tupelo to Lowell (Indiana) | 490.45 mi (789.31 km) |
| Tupelo to Lowell (Massachusetts) | 1,102.08 mi (1,773.63 km) |
| Tupelo to Lower Burrell (Pennsylvania) | 658.93 mi (1,060.45 km) |
| Tupelo to Lowes Island (Virginia) | 711.14 mi (1,144.47 km) |
| Tupelo to Lubbock (Texas) | 755.36 mi (1,215.64 km) |
| Tupelo to Lufkin (Texas) | 403.31 mi (649.06 km) |
| Tupelo to Luling (Louisiana) | 316.37 mi (509.15 km) |
| Tupelo to Lumberton (North Carolina) | 553.77 mi (891.20 km) |
| Tupelo to Lumberton (Texas) | 423.20 mi (681.07 km) |
| Tupelo to Lutz (Florida) | 563.04 mi (906.12 km) |
| Tupelo to Lynbrook (New York) | 934.54 mi (1,504.00 km) |
| Tupelo to Lynchburg (Virginia) | 576.20 mi (927.31 km) |
| Tupelo to Lynden (Washington) | 1,992.14 mi (3,206.04 km) |
| Tupelo to Lyndhurst (Ohio) | 637.14 mi (1,025.38 km) |
