| Tupelo to Isabela (Puerto Rico) | 1,722.98 mi (2,772.87 km) |
| Tupelo to Iselin (New Jersey) | 901.23 mi (1,450.39 km) |
| Tupelo to Isla Vista (California) | 1,768.88 mi (2,846.75 km) |
| Tupelo to Issaquah (Washington) | 1,945.90 mi (3,131.63 km) |
| Tupelo to Ithaca (New York) | 869.04 mi (1,398.58 km) |
| Tupelo to Ives Estates (Florida) | 767.70 mi (1,235.49 km) |
| Tupelo to Jackson (Michigan) | 598.68 mi (963.48 km) |
| Tupelo to Jackson (Mississippi) | 159.78 mi (257.14 km) |
| Tupelo to Jackson (Missouri) | 220.98 mi (355.63 km) |
| Tupelo to Jackson (Tennessee) | 95.85 mi (154.25 km) |
| Tupelo to Jackson (Wyoming) | 1,339.60 mi (2,155.88 km) |
| Tupelo to Jacksonville (Alabama) | 173.40 mi (279.06 km) |
| Tupelo to Jacksonville (Arkansas) | 197.90 mi (318.49 km) |
| Tupelo to Jacksonville (Florida) | 493.60 mi (794.37 km) |
| Tupelo to Jacksonville (Illinois) | 386.20 mi (621.53 km) |
