| Tupelo to Indianapolis (Indiana) | 406.36 mi (653.98 km) |
| Tupelo to Indianola (Iowa) | 556.38 mi (895.41 km) |
| Tupelo to Indio (California) | 1,570.97 mi (2,528.23 km) |
| Tupelo to Inglewood (California) | 1,688.08 mi (2,716.70 km) |
| Tupelo to Inkster (Michigan) | 627.12 mi (1,009.25 km) |
| Tupelo to Inver Grove Heights (Minnesota) | 764.59 mi (1,230.49 km) |
| Tupelo to Inwood (New York) | 929.88 mi (1,496.49 km) |
| Tupelo to Iona (Florida) | 670.29 mi (1,078.73 km) |
| Tupelo to Ionia (Michigan) | 633.09 mi (1,018.85 km) |
| Tupelo to Iowa City (Iowa) | 532.57 mi (857.08 km) |
| Tupelo to Irmo (South Carolina) | 430.79 mi (693.29 km) |
| Tupelo to Irondale (Alabama) | 128.91 mi (207.46 km) |
| Tupelo to Ironton (Ohio) | 447.14 mi (719.60 km) |
| Tupelo to Irvine (California) | 1,658.91 mi (2,669.75 km) |
| Tupelo to Irving (Texas) | 484.08 mi (779.05 km) |
