| Tupelo to Eatontown (New Jersey) | 906.18 mi (1,458.35 km) |
| Tupelo to Eau Claire (Wisconsin) | 743.56 mi (1,196.64 km) |
| Tupelo to Echelon (New Jersey) | 848.52 mi (1,365.55 km) |
| Tupelo to Eden (North Carolina) | 529.18 mi (851.64 km) |
| Tupelo to Eden Prairie (Minnesota) | 772.78 mi (1,243.67 km) |
| Tupelo to Edgewater (Florida) | 586.81 mi (944.38 km) |
| Tupelo to Edgewater (New Jersey) | 924.86 mi (1,488.41 km) |
| Tupelo to Edgewood (Maryland) | 773.22 mi (1,244.38 km) |
| Tupelo to Edgewood (Washington) | 1,950.76 mi (3,139.45 km) |
| Tupelo to Edina (Minnesota) | 773.85 mi (1,245.39 km) |
| Tupelo to Edinburg (Texas) | 785.39 mi (1,263.96 km) |
| Tupelo to Edmond (Oklahoma) | 500.93 mi (806.17 km) |
| Tupelo to Edmonds (Washington) | 1,964.69 mi (3,161.86 km) |
| Tupelo to Edwards (Colorado) | 1,052.38 mi (1,693.65 km) |
| Tupelo to Edwardsville (Illinois) | 320.18 mi (515.28 km) |
