| Tupelo to Duluth (Minnesota) | 882.21 mi (1,419.79 km) |
| Tupelo to Dumas (Texas) | 755.77 mi (1,216.29 km) |
| Tupelo to Dumont (New Jersey) | 927.52 mi (1,492.69 km) |
| Tupelo to Duncan (Oklahoma) | 524.03 mi (843.34 km) |
| Tupelo to Duncanville (Texas) | 484.58 mi (779.86 km) |
| Tupelo to Dundalk (Maryland) | 759.44 mi (1,222.20 km) |
| Tupelo to Dunedin (Florida) | 555.86 mi (894.56 km) |
| Tupelo to Dunkirk (New York) | 761.29 mi (1,225.18 km) |
| Tupelo to Dunmore (Pennsylvania) | 868.27 mi (1,397.34 km) |
| Tupelo to Dunwoody (Georgia) | 253.83 mi (408.51 km) |
| Tupelo to Durango (Colorado) | 1,091.17 mi (1,756.07 km) |
| Tupelo to Durant (Oklahoma) | 438.42 mi (705.57 km) |
| Tupelo to Durham (North Carolina) | 567.64 mi (913.53 km) |
| Tupelo to Dyer (Indiana) | 503.86 mi (810.88 km) |
| Tupelo to Dyersburg (Tennessee) | 128.10 mi (206.16 km) |
