| Tupelo to Darby (Pennsylvania) | 837.55 mi (1,347.91 km) |
| Tupelo to Dardenne Prairie (Missouri) | 329.31 mi (529.97 km) |
| Tupelo to Darien (Illinois) | 518.12 mi (833.83 km) |
| Tupelo to Davenport (Iowa) | 513.72 mi (826.75 km) |
| Tupelo to Davidson (North Carolina) | 455.86 mi (733.63 km) |
| Tupelo to Davie (Florida) | 757.42 mi (1,218.95 km) |
| Tupelo to Davis (California) | 1,848.83 mi (2,975.41 km) |
| Tupelo to Dayton (Nevada) | 1,732.36 mi (2,787.97 km) |
| Tupelo to Dayton (Ohio) | 455.35 mi (732.82 km) |
| Tupelo to Daytona Beach (Florida) | 568.82 mi (915.43 km) |
| Tupelo to De Pere (Wisconsin) | 702.96 mi (1,131.30 km) |
| Tupelo to De Witt (New York) | 910.46 mi (1,465.25 km) |
| Tupelo to Dearborn (Michigan) | 630.86 mi (1,015.27 km) |
| Tupelo to Dearborn Heights (Michigan) | 629.45 mi (1,013.00 km) |
| Tupelo to DeBary (Florida) | 573.01 mi (922.18 km) |
