| Tupelo to Cloverleaf (Texas) | 487.84 mi (785.10 km) |
| Tupelo to Cloverly (Maryland) | 730.11 mi (1,175.00 km) |
| Tupelo to Clovis (California) | 1,741.30 mi (2,802.35 km) |
| Tupelo to Clovis (New Mexico) | 824.23 mi (1,326.47 km) |
| Tupelo to Clute (Texas) | 533.57 mi (858.70 km) |
| Tupelo to Coachella (California) | 1,566.26 mi (2,520.65 km) |
| Tupelo to Coalinga (California) | 1,780.41 mi (2,865.30 km) |
| Tupelo to Coamo (Puerto Rico) | 1,774.40 mi (2,855.63 km) |
| Tupelo to Coatesville (Pennsylvania) | 812.38 mi (1,307.40 km) |
| Tupelo to Cockeysville (Maryland) | 758.72 mi (1,221.04 km) |
| Tupelo to Cocoa (Florida) | 621.22 mi (999.75 km) |
| Tupelo to Cocoa Beach (Florida) | 629.78 mi (1,013.54 km) |
| Tupelo to Coconut Creek (Florida) | 750.89 mi (1,208.45 km) |
| Tupelo to Coeur d'Alene (Idaho) | 1,718.43 mi (2,765.54 km) |
| Tupelo to Cohoes (New York) | 999.93 mi (1,609.22 km) |
