| Tupelo to Clarksdale (Mississippi) | 105.10 mi (169.14 km) |
| Tupelo to Clarkston (Georgia) | 259.07 mi (416.93 km) |
| Tupelo to Clarksville (Indiana) | 325.01 mi (523.06 km) |
| Tupelo to Clarksville (Tennessee) | 177.15 mi (285.09 km) |
| Tupelo to Clawson (Michigan) | 645.87 mi (1,039.43 km) |
| Tupelo to Clay (Alabama) | 127.92 mi (205.87 km) |
| Tupelo to Clayton (California) | 1,860.59 mi (2,994.33 km) |
| Tupelo to Clayton (Missouri) | 315.06 mi (507.04 km) |
| Tupelo to Clayton (North Carolina) | 589.77 mi (949.15 km) |
| Tupelo to Clayton (Ohio) | 456.58 mi (734.80 km) |
| Tupelo to Clearfield (Utah) | 1,353.19 mi (2,177.76 km) |
| Tupelo to Clearlake (California) | 1,896.65 mi (3,052.36 km) |
| Tupelo to Clearwater (Florida) | 559.70 mi (900.74 km) |
| Tupelo to Cleburne (Texas) | 518.30 mi (834.13 km) |
| Tupelo to Clemmons (North Carolina) | 486.78 mi (783.39 km) |
