| Tupelo to Anoka (Minnesota) | 795.03 mi (1,279.48 km) |
| Tupelo to Ansonia (Connecticut) | 982.71 mi (1,581.51 km) |
| Tupelo to Antelope (California) | 1,828.39 mi (2,942.51 km) |
| Tupelo to Anthem (Arizona) | 1,335.88 mi (2,149.89 km) |
| Tupelo to Antioch (California) | 1,853.18 mi (2,982.41 km) |
| Tupelo to Antioch (Illinois) | 568.03 mi (914.16 km) |
| Tupelo to Apache Junction (Arizona) | 1,307.39 mi (2,104.04 km) |
| Tupelo to Apex (North Carolina) | 566.66 mi (911.95 km) |
| Tupelo to Apollo Beach (Florida) | 585.12 mi (941.66 km) |
| Tupelo to Apopka (Florida) | 572.37 mi (921.13 km) |
| Tupelo to Apple Valley (California) | 1,618.23 mi (2,604.28 km) |
| Tupelo to Apple Valley (Minnesota) | 761.72 mi (1,225.87 km) |
| Tupelo to Appleton (Wisconsin) | 691.78 mi (1,113.32 km) |
| Tupelo to Arbutus (Maryland) | 748.96 mi (1,205.34 km) |
| Tupelo to Arcadia (California) | 1,668.81 mi (2,685.69 km) |
