| Tupelo to Altus (Oklahoma) | 602.70 mi (969.96 km) |
| Tupelo to Alum Rock (California) | 1,856.80 mi (2,988.23 km) |
| Tupelo to Alvin (Texas) | 511.79 mi (823.65 km) |
| Tupelo to Amarillo (Texas) | 746.05 mi (1,200.64 km) |
| Tupelo to Amelia (Ohio) | 412.87 mi (664.44 km) |
| Tupelo to American Canyon (California) | 1,877.78 mi (3,022.00 km) |
| Tupelo to American Fork (Utah) | 1,331.08 mi (2,142.17 km) |
| Tupelo to Americus (Georgia) | 301.54 mi (485.28 km) |
| Tupelo to Ames (Iowa) | 597.89 mi (962.22 km) |
| Tupelo to Amherst (Ohio) | 606.84 mi (976.61 km) |
| Tupelo to Ammon (Idaho) | 1,395.33 mi (2,245.57 km) |
| Tupelo to Amsterdam (New York) | 985.28 mi (1,585.66 km) |
| Tupelo to Anacortes (Washington) | 1,990.16 mi (3,202.85 km) |
| Tupelo to Anaheim (California) | 1,661.81 mi (2,674.43 km) |
| Tupelo to Anchorage (Alaska) | 3,202.25 mi (5,153.52 km) |
