| Tupelo to Sangeorgiu de Mures | 5,482.16 mi (8,822.69 km) |
| Tupelo to Sangeorz-Bai | 5,453.98 mi (8,777.33 km) |
| Tupelo to Sannicolau Mare | 5,358.36 mi (8,623.45 km) |
| Tupelo to Santana | 5,380.15 mi (8,658.52 km) |
| Tupelo to Satu Mare | 5,370.77 mi (8,643.42 km) |
| Tupelo to Scobinti | 5,533.99 mi (8,906.09 km) |
| Tupelo to Scornicesti | 5,572.38 mi (8,967.87 km) |
| Tupelo to Sebes | 5,474.67 mi (8,810.62 km) |
| Tupelo to Seini | 5,386.98 mi (8,669.51 km) |
| Tupelo to Sfantu-Gheorghe | 5,561.03 mi (8,949.62 km) |
| Tupelo to Sibiu | 5,503.67 mi (8,857.31 km) |
| Tupelo to Sighetu Marmatiei | 5,401.19 mi (8,692.38 km) |
| Tupelo to Sighisoara | 5,508.73 mi (8,865.45 km) |
| Tupelo to Simeria | 5,458.42 mi (8,784.47 km) |
| Tupelo to Sinaia | 5,575.27 mi (8,972.54 km) |
