| The Woodlands to Scottsbluff (Nebraska) | 926.41 mi (1,490.92 km) |
| The Woodlands to Scottsboro (Alabama) | 632.16 mi (1,017.36 km) |
| The Woodlands to Scottsdale (Arizona) | 987.89 mi (1,589.86 km) |
| The Woodlands to Scranton (Pennsylvania) | 1,351.00 mi (2,174.23 km) |
| The Woodlands to Seabrook (Maryland) | 1,220.19 mi (1,963.71 km) |
| The Woodlands to Seabrook (Texas) | 50.72 mi (81.63 km) |
| The Woodlands to Seaford (New York) | 1,430.33 mi (2,301.89 km) |
| The Woodlands to Seagoville (Texas) | 181.78 mi (292.55 km) |
| The Woodlands to Seal Beach (California) | 1,342.40 mi (2,160.38 km) |
| The Woodlands to Searcy (Arkansas) | 413.27 mi (665.09 km) |
| The Woodlands to Seaside (California) | 1,575.80 mi (2,536.01 km) |
| The Woodlands to SeaTac (Washington) | 1,855.26 mi (2,985.76 km) |
| The Woodlands to Seattle (Washington) | 1,862.50 mi (2,997.41 km) |
| The Woodlands to Sebastian (Florida) | 922.73 mi (1,484.99 km) |
| The Woodlands to Sebring (Florida) | 870.63 mi (1,401.14 km) |
