| Tarpon Springs to Southchase (Florida) | 84.99 mi (136.78 km) |
| Tarpon Springs to Southern Pines (North Carolina) | 525.09 mi (845.06 km) |
| Tarpon Springs to Southfield (Michigan) | 990.31 mi (1,593.74 km) |
| Tarpon Springs to Southgate (Michigan) | 971.45 mi (1,563.40 km) |
| Tarpon Springs to Southlake (Texas) | 917.20 mi (1,476.09 km) |
| Tarpon Springs to Spanaway (Washington) | 2,496.50 mi (4,017.73 km) |
| Tarpon Springs to Spanish Fork (Utah) | 1,835.41 mi (2,953.81 km) |
| Tarpon Springs to Spanish Lake (Missouri) | 850.41 mi (1,368.61 km) |
| Tarpon Springs to Spanish Springs (Nevada) | 2,242.00 mi (3,608.16 km) |
| Tarpon Springs to Sparks (Nevada) | 2,243.54 mi (3,610.62 km) |
| Tarpon Springs to Spartanburg (South Carolina) | 472.06 mi (759.70 km) |
| Tarpon Springs to Spearfish (South Dakota) | 1,618.18 mi (2,604.20 km) |
| Tarpon Springs to Speedway (Indiana) | 828.77 mi (1,333.78 km) |
| Tarpon Springs to Spencer (Iowa) | 1,245.02 mi (2,003.67 km) |
| Tarpon Springs to Spokane (Washington) | 2,291.45 mi (3,687.73 km) |
