| Tarpon Springs to Scottsbluff (Nebraska) | 1,508.52 mi (2,427.72 km) |
| Tarpon Springs to Scottsboro (Alabama) | 488.72 mi (786.51 km) |
| Tarpon Springs to Scottsdale (Arizona) | 1,760.76 mi (2,833.67 km) |
| Tarpon Springs to Scranton (Pennsylvania) | 999.58 mi (1,608.67 km) |
| Tarpon Springs to Seabrook (Maryland) | 821.61 mi (1,322.25 km) |
| Tarpon Springs to Seabrook (Texas) | 748.08 mi (1,203.92 km) |
| Tarpon Springs to Seaford (New York) | 1,012.17 mi (1,628.93 km) |
| Tarpon Springs to Seagoville (Texas) | 877.48 mi (1,412.17 km) |
| Tarpon Springs to Seal Beach (California) | 2,117.19 mi (3,407.29 km) |
| Tarpon Springs to Searcy (Arkansas) | 719.36 mi (1,157.69 km) |
| Tarpon Springs to Seaside (California) | 2,335.72 mi (3,758.98 km) |
| Tarpon Springs to SeaTac (Washington) | 2,498.19 mi (4,020.45 km) |
| Tarpon Springs to Seattle (Washington) | 2,503.12 mi (4,028.38 km) |
| Tarpon Springs to Sebastian (Florida) | 141.45 mi (227.64 km) |
| Tarpon Springs to Sebring (Florida) | 92.52 mi (148.89 km) |
