| Tarpon Springs to Oskaloosa (Iowa) | 1,065.69 mi (1,715.06 km) |
| Tarpon Springs to Oswego (Illinois) | 986.42 mi (1,587.50 km) |
| Tarpon Springs to Oswego (New York) | 1,113.13 mi (1,791.41 km) |
| Tarpon Springs to Otsego (Minnesota) | 1,323.93 mi (2,130.65 km) |
| Tarpon Springs to Ottawa (Illinois) | 974.56 mi (1,568.40 km) |
| Tarpon Springs to Ottawa (Kansas) | 1,018.67 mi (1,639.39 km) |
| Tarpon Springs to Ottumwa (Iowa) | 1,043.63 mi (1,679.55 km) |
| Tarpon Springs to Overland (Missouri) | 849.79 mi (1,367.61 km) |
| Tarpon Springs to Overland Park (Kansas) | 1,009.23 mi (1,624.19 km) |
| Tarpon Springs to Overlea (Maryland) | 853.30 mi (1,373.25 km) |
| Tarpon Springs to Oviedo (Florida) | 101.98 mi (164.11 km) |
| Tarpon Springs to Owasso (Oklahoma) | 947.05 mi (1,524.13 km) |
| Tarpon Springs to Owatonna (Minnesota) | 1,244.42 mi (2,002.70 km) |
| Tarpon Springs to Owensboro (Kentucky) | 710.01 mi (1,142.65 km) |
| Tarpon Springs to Owings Mills (Maryland) | 849.81 mi (1,367.63 km) |
