| Tarpon Springs to Olympia (Washington) | 2,516.61 mi (4,050.10 km) |
| Tarpon Springs to Olympia Heights (Florida) | 224.41 mi (361.15 km) |
| Tarpon Springs to Omaha (Nebraska) | 1,176.39 mi (1,893.22 km) |
| Tarpon Springs to On Top of the World Designated Place (Florida) | 72.11 mi (116.05 km) |
| Tarpon Springs to Onalaska (Wisconsin) | 1,183.86 mi (1,905.24 km) |
| Tarpon Springs to Oneida (New York) | 1,104.75 mi (1,777.92 km) |
| Tarpon Springs to Oneonta (New York) | 1,078.31 mi (1,735.38 km) |
| Tarpon Springs to Ontario (California) | 2,090.95 mi (3,365.06 km) |
| Tarpon Springs to Ontario (Oregon) | 2,180.22 mi (3,508.73 km) |
| Tarpon Springs to Opa-locka (Florida) | 219.01 mi (352.47 km) |
| Tarpon Springs to Opelika (Alabama) | 348.47 mi (560.81 km) |
| Tarpon Springs to Opelousas (Louisiana) | 584.62 mi (940.85 km) |
| Tarpon Springs to Orange (California) | 2,102.92 mi (3,384.32 km) |
| Tarpon Springs to Orange (Texas) | 677.32 mi (1,090.04 km) |
| Tarpon Springs to Orange City (Florida) | 104.65 mi (168.42 km) |
