| Tamiami to Southchase (Florida) | 191.21 mi (307.72 km) |
| Tamiami to Southern Pines (North Carolina) | 654.73 mi (1,053.68 km) |
| Tamiami to Southfield (Michigan) | 1,166.62 mi (1,877.50 km) |
| Tamiami to Southgate (Michigan) | 1,147.64 mi (1,846.94 km) |
| Tamiami to Southlake (Texas) | 1,122.67 mi (1,806.76 km) |
| Tamiami to Spanaway (Washington) | 2,715.71 mi (4,370.52 km) |
| Tamiami to Spanish Fork (Utah) | 2,049.86 mi (3,298.92 km) |
| Tamiami to Spanish Lake (Missouri) | 1,065.69 mi (1,715.06 km) |
| Tamiami to Spanish Springs (Nevada) | 2,452.65 mi (3,947.16 km) |
| Tamiami to Sparks (Nevada) | 2,454.00 mi (3,949.34 km) |
| Tamiami to Spartanburg (South Carolina) | 641.31 mi (1,032.09 km) |
| Tamiami to Spearfish (South Dakota) | 1,838.29 mi (2,958.44 km) |
| Tamiami to Speedway (Indiana) | 1,027.04 mi (1,652.86 km) |
| Tamiami to Spencer (Iowa) | 1,461.46 mi (2,352.00 km) |
| Tamiami to Spokane (Washington) | 2,511.44 mi (4,041.77 km) |
