| Tamiami to Scottsbluff (Nebraska) | 1,728.30 mi (2,781.43 km) |
| Tamiami to Scottsboro (Alabama) | 700.28 mi (1,126.99 km) |
| Tamiami to Scottsdale (Arizona) | 1,957.25 mi (3,149.88 km) |
| Tamiami to Scranton (Pennsylvania) | 1,114.59 mi (1,793.75 km) |
| Tamiami to Seabrook (Maryland) | 936.71 mi (1,507.50 km) |
| Tamiami to Seabrook (Texas) | 932.09 mi (1,500.05 km) |
| Tamiami to Seaford (New York) | 1,104.08 mi (1,776.84 km) |
| Tamiami to Seagoville (Texas) | 1,082.31 mi (1,741.81 km) |
| Tamiami to Seal Beach (California) | 2,312.55 mi (3,721.70 km) |
| Tamiami to Searcy (Arkansas) | 939.33 mi (1,511.70 km) |
| Tamiami to Seaside (California) | 2,538.99 mi (4,086.11 km) |
| Tamiami to SeaTac (Washington) | 2,717.61 mi (4,373.57 km) |
| Tamiami to Seattle (Washington) | 2,722.62 mi (4,381.63 km) |
| Tamiami to Sebastian (Florida) | 140.11 mi (225.49 km) |
| Tamiami to Sebring (Florida) | 135.51 mi (218.09 km) |
