| Talladega to Sunset (Florida) | 635.52 mi (1,022.78 km) |
| Talladega to Superior (Colorado) | 1,144.65 mi (1,842.13 km) |
| Talladega to Superior (Wisconsin) | 968.59 mi (1,558.79 km) |
| Talladega to Surprise (Arizona) | 1,513.29 mi (2,435.40 km) |
| Talladega to Susanville (California) | 1,953.12 mi (3,143.24 km) |
| Talladega to Sussex (Wisconsin) | 680.05 mi (1,094.44 km) |
| Talladega to Suwanee (Georgia) | 124.19 mi (199.86 km) |
| Talladega to Swansea (Illinois) | 414.91 mi (667.74 km) |
| Talladega to Sweetwater (Florida) | 630.51 mi (1,014.70 km) |
| Talladega to Sweetwater (Texas) | 831.72 mi (1,338.52 km) |
| Talladega to Sycamore (Illinois) | 608.14 mi (978.70 km) |
| Talladega to Sylacauga (Alabama) | 19.96 mi (32.13 km) |
| Talladega to Sylvania (Ohio) | 586.57 mi (944.00 km) |
| Talladega to Syosset (New York) | 859.78 mi (1,383.67 km) |
| Talladega to Syracuse (New York) | 854.56 mi (1,375.28 km) |
