| Talladega to Smithville (Missouri) | 625.26 mi (1,006.26 km) |
| Talladega to Smyrna (Delaware) | 709.58 mi (1,141.95 km) |
| Talladega to Smyrna (Georgia) | 95.71 mi (154.03 km) |
| Talladega to Smyrna (Tennessee) | 176.86 mi (284.62 km) |
| Talladega to Snellville (Georgia) | 123.98 mi (199.53 km) |
| Talladega to Snoqualmie (Washington) | 2,090.69 mi (3,364.65 km) |
| Talladega to Snyder (Texas) | 858.36 mi (1,381.40 km) |
| Talladega to Socastee (South Carolina) | 408.51 mi (657.43 km) |
| Talladega to Socorro (Texas) | 1,179.06 mi (1,897.52 km) |
| Talladega to Soddy-Daisy (Tennessee) | 136.61 mi (219.85 km) |
| Talladega to Solana Beach (California) | 1,794.61 mi (2,888.15 km) |
| Talladega to Soledad (California) | 1,995.96 mi (3,212.19 km) |
| Talladega to Solon (Ohio) | 605.83 mi (974.99 km) |
| Talladega to Somers Point (New Jersey) | 756.66 mi (1,217.72 km) |
| Talladega to Somerset (Kentucky) | 265.79 mi (427.74 km) |
