| Talladega to Oskaloosa (Iowa) | 650.61 mi (1,047.06 km) |
| Talladega to Oswego (Illinois) | 583.00 mi (938.25 km) |
| Talladega to Oswego (New York) | 864.11 mi (1,390.66 km) |
| Talladega to Otsego (Minnesota) | 909.99 mi (1,464.48 km) |
| Talladega to Ottawa (Illinois) | 567.39 mi (913.13 km) |
| Talladega to Ottawa (Kansas) | 623.79 mi (1,003.89 km) |
| Talladega to Ottumwa (Iowa) | 628.57 mi (1,011.59 km) |
| Talladega to Overland (Missouri) | 434.76 mi (699.68 km) |
| Talladega to Overland Park (Kansas) | 609.03 mi (980.14 km) |
| Talladega to Overlea (Maryland) | 671.52 mi (1,080.71 km) |
| Talladega to Oviedo (Florida) | 439.63 mi (707.51 km) |
| Talladega to Owasso (Oklahoma) | 585.63 mi (942.48 km) |
| Talladega to Owatonna (Minnesota) | 829.82 mi (1,335.47 km) |
| Talladega to Owensboro (Kentucky) | 304.20 mi (489.56 km) |
| Talladega to Owings Mills (Maryland) | 661.46 mi (1,064.51 km) |
