| Talavera de la Reina to Sangeorgiu de Mures | 1,533.00 mi (2,467.13 km) |
| Talavera de la Reina to Sangeorz-Bai | 1,550.39 mi (2,495.12 km) |
| Talavera de la Reina to Sannicolau Mare | 1,346.19 mi (2,166.49 km) |
| Talavera de la Reina to Santana | 1,391.22 mi (2,238.95 km) |
| Talavera de la Reina to Satu Mare | 1,473.15 mi (2,370.80 km) |
| Talavera de la Reina to Scobinti | 1,655.07 mi (2,663.57 km) |
| Talavera de la Reina to Scornicesti | 1,527.07 mi (2,457.59 km) |
| Talavera de la Reina to Sebes | 1,485.94 mi (2,391.39 km) |
| Talavera de la Reina to Seini | 1,490.61 mi (2,398.90 km) |
| Talavera de la Reina to Sfantu-Gheorghe | 1,591.58 mi (2,561.40 km) |
| Talavera de la Reina to Sibiu | 1,512.69 mi (2,434.44 km) |
| Talavera de la Reina to Sighetu Marmatiei | 1,520.59 mi (2,447.16 km) |
| Talavera de la Reina to Sighisoara | 1,545.94 mi (2,487.95 km) |
| Talavera de la Reina to Simeria | 1,458.36 mi (2,347.01 km) |
| Talavera de la Reina to Sinaia | 1,578.13 mi (2,539.75 km) |
