| Talavera de la Reina to Sierpc | 1,457.15 mi (2,345.06 km) |
| Talavera de la Reina to Skarzysko-Kamienna | 1,453.87 mi (2,339.77 km) |
| Talavera de la Reina to Skawina | 1,381.09 mi (2,222.65 km) |
| Talavera de la Reina to Skierniewice | 1,447.10 mi (2,328.88 km) |
| Talavera de la Reina to Skoczow | 1,333.15 mi (2,145.50 km) |
| Talavera de la Reina to Skwierzyna | 1,297.73 mi (2,088.50 km) |
| Talavera de la Reina to Slawno | 1,407.24 mi (2,264.73 km) |
| Talavera de la Reina to Slubice | 1,255.61 mi (2,020.71 km) |
| Talavera de la Reina to Slupca | 1,371.53 mi (2,207.27 km) |
| Talavera de la Reina to Slupsk | 1,423.13 mi (2,290.30 km) |
| Talavera de la Reina to Sochaczew | 1,458.18 mi (2,346.71 km) |
| Talavera de la Reina to Sokolka | 1,615.74 mi (2,600.28 km) |
| Talavera de la Reina to Sokolow Podlaski | 1,540.53 mi (2,479.24 km) |
| Talavera de la Reina to Solec Kujawski | 1,411.92 mi (2,272.27 km) |
| Talavera de la Reina to Sopot | 1,473.42 mi (2,371.24 km) |
