| Talavera de la Reina to Ede | 973.42 mi (1,566.57 km) |
| Talavera de la Reina to Eemnes | 974.92 mi (1,568.98 km) |
| Talavera de la Reina to Eerbeek | 986.31 mi (1,587.31 km) |
| Talavera de la Reina to Eersel | 925.30 mi (1,489.12 km) |
| Talavera de la Reina to Eijsden | 903.94 mi (1,454.75 km) |
| Talavera de la Reina to Eindhoven | 934.17 mi (1,503.40 km) |
| Talavera de la Reina to Elburg | 1,000.54 mi (1,610.21 km) |
| Talavera de la Reina to Emmeloord | 1,013.03 mi (1,630.32 km) |
| Talavera de la Reina to Emmen | 1,044.93 mi (1,681.64 km) |
| Talavera de la Reina to Enkhuizen | 1,002.14 mi (1,612.79 km) |
| Talavera de la Reina to Enschede | 1,013.80 mi (1,631.55 km) |
| Talavera de la Reina to Epe | 998.09 mi (1,606.27 km) |
| Talavera de la Reina to Ermelo | 986.42 mi (1,587.49 km) |
| Talavera de la Reina to Etten-Leur | 921.02 mi (1,482.24 km) |
| Talavera de la Reina to Franeker | 1,036.52 mi (1,668.11 km) |
