| Talavera de la Reina to Spello | 928.23 mi (1,493.85 km) |
| Talavera de la Reina to Spilamberto | 868.32 mi (1,397.43 km) |
| Talavera de la Reina to Spilimbergo | 988.13 mi (1,590.24 km) |
| Talavera de la Reina to Spinea | 941.07 mi (1,514.51 km) |
| Talavera de la Reina to Spoleto | 927.06 mi (1,491.96 km) |
| Talavera de la Reina to Spoltore | 999.01 mi (1,607.75 km) |
| Talavera de la Reina to Spresiano | 951.51 mi (1,531.32 km) |
| Talavera de la Reina to Squinzano | 1,204.74 mi (1,938.84 km) |
| Talavera de la Reina to Statte | 1,159.40 mi (1,865.87 km) |
| Talavera de la Reina to Stezzano | 831.26 mi (1,337.78 km) |
| Talavera de la Reina to Strada | 867.44 mi (1,396.02 km) |
| Talavera de la Reina to Stradella | 800.58 mi (1,288.42 km) |
| Talavera de la Reina to Striano | 1,020.57 mi (1,642.45 km) |
| Talavera de la Reina to Subiaco | 944.00 mi (1,519.21 km) |
| Talavera de la Reina to Sulmona | 986.70 mi (1,587.94 km) |
