| Talavera de la Reina to Savignano sul Rubicone | 927.02 mi (1,491.90 km) |
| Talavera de la Reina to Savona | 744.30 mi (1,197.83 km) |
| Talavera de la Reina to Scafati | 1,018.65 mi (1,639.35 km) |
| Talavera de la Reina to Scalea | 1,091.46 mi (1,756.53 km) |
| Talavera de la Reina to Scandiano | 853.92 mi (1,374.24 km) |
| Talavera de la Reina to Scandicci | 863.61 mi (1,389.85 km) |
| Talavera de la Reina to Schio | 909.21 mi (1,463.23 km) |
| Talavera de la Reina to Sciacca | 978.90 mi (1,575.38 km) |
| Talavera de la Reina to Scicli | 1,078.22 mi (1,735.23 km) |
| Talavera de la Reina to Scordia | 1,075.86 mi (1,731.43 km) |
| Talavera de la Reina to Scorze | 940.39 mi (1,513.41 km) |
| Talavera de la Reina to Sedico | 952.50 mi (1,532.90 km) |
| Talavera de la Reina to Sedriano | 796.20 mi (1,281.36 km) |
| Talavera de la Reina to Segni | 939.15 mi (1,511.42 km) |
| Talavera de la Reina to Segrate | 810.99 mi (1,305.16 km) |
