| Talavera de la Reina to Sacile | 967.02 mi (1,556.27 km) |
| Talavera de la Reina to Sala Consilina | 1,076.66 mi (1,732.72 km) |
| Talavera de la Reina to Salemi | 958.16 mi (1,542.00 km) |
| Talavera de la Reina to Salerno | 1,031.20 mi (1,659.56 km) |
| Talavera de la Reina to Salo | 869.34 mi (1,399.07 km) |
| Talavera de la Reina to Salsomaggiore Terme | 825.45 mi (1,328.44 km) |
| Talavera de la Reina to Saluzzo | 707.10 mi (1,137.97 km) |
| Talavera de la Reina to Salzano | 939.91 mi (1,512.65 km) |
| Talavera de la Reina to Samarate | 791.90 mi (1,274.44 km) |
| Talavera de la Reina to San Benedetto del Tronto | 988.78 mi (1,591.29 km) |
| Talavera de la Reina to San Biagio di Callalta | 955.39 mi (1,537.55 km) |
| Talavera de la Reina to San Bonifacio | 898.70 mi (1,446.32 km) |
| Talavera de la Reina to San Casciano in Val di Pesa | 862.04 mi (1,387.32 km) |
| Talavera de la Reina to San Cataldo | 1,026.63 mi (1,652.21 km) |
| Talavera de la Reina to San Cesareo | 928.26 mi (1,493.90 km) |
