| Syston to Enumclaw (Washington) | 4,708.68 mi (7,577.89 km) |
| Syston to Ephrata (Pennsylvania) | 3,508.65 mi (5,646.62 km) |
| Syston to Erie (Colorado) | 4,590.05 mi (7,386.96 km) |
| Syston to Erie (Pennsylvania) | 3,574.54 mi (5,752.66 km) |
| Syston to Erlanger (Kentucky) | 3,894.08 mi (6,266.92 km) |
| Syston to Escanaba (Michigan) | 3,674.89 mi (5,914.16 km) |
| Syston to Escondido (California) | 5,371.00 mi (8,643.79 km) |
| Syston to Española (New Mexico) | 4,841.54 mi (7,791.71 km) |
| Syston to Essex (Maryland) | 3,559.19 mi (5,727.96 km) |
| Syston to Essex Junction (Vermont) | 3,199.48 mi (5,149.06 km) |
| Syston to Estelle (Louisiana) | 4,568.38 mi (7,352.10 km) |
| Syston to Estero (Florida) | 4,407.77 mi (7,093.61 km) |
| Syston to Euclid (Ohio) | 3,654.50 mi (5,881.35 km) |
| Syston to Eufaula (Alabama) | 4,265.16 mi (6,864.12 km) |
| Syston to Eugene (Oregon) | 4,920.03 mi (7,918.02 km) |
